Characteristic symptoms, psoriasis, preventive symmetrically on the extensor skin surface of the popular location, hand and foot, and scalp.
Although a leading role-plays in the development the presence of psoriasis, genetic predisposition (disease related to psoriasis, a disease, hereditary), EXO and endogenous factors, many of which can serve to push the emergence of disease (psoriasis, developmental, nervous, soil, ground, endocrine disorders, infectious disease, etc.).
A reason for the development of the disease
Is disease, sexual predisposition, thus the frequency of psoriasis in both men and women are not that different. The patient first develops the disease, 12 per cent a decade or so. Developing psoriasis for twenty years and forty-six patients, thirty – year- sixty percent.
Two years in the development of psoriasis Summit pointed out:
- twenty-seven, fifty-four years for men;
- fifteen and fifty-four years women.
Causes of psoriasis in adults with
The exact cause of psoriasis is unknown. The leading role for the pathogenesis of the disease genetic predisposition. In addition, the view that instability plays an important role in immunological, lipid abnormalities, and the presence of the patient foci of chronic infection.
The theory in favor of genetic (hereditary causes psoriasis is a disease the truth is always close only the patient, but also his close relatives.
It is possible for a psoriasis susceptibility, while the classic genome analysis. There may be hereditary predisposition to the disease loci responsible for these patients, ten chromosomes (1 to 9 SPORTS, and HLA – B27, 17, etc.).
The most obvious host genome responsible for innate predisposition, illness, I believe PSORS1.
In addition, genetically plays an important role in the pathogenesis of psoriasis, resulting in metabolism disorders of carbohydrates and lipids. Hyperlipidemia occur in most patients with severe psoriasis and metabolic syndrome. In this context, celebrated in patients with psoriasis with a high risk of heavy early atherosclerotic vascular and cardiovascular pathologies.
This hyperlipidemia, notes, LCD disturbed metabolism (fatty acids), increased production of radical compounds from freely participating in keratinlesme epidermis, etc.
In the study, psoriatic plaques plaques, taped them great content, oxidized low-density lipoprotein.
Marks the main, let, appreciated an outbreak of psoriasis keratinocytes proliferation, Ki67 and keratin protein six, sixteen, seventeen. The expression of these markers is responsible for the process of growth, differentiation disorders, cell growth and inflammatory reactions in the dermis.
Therefore, during the phase of clinical improvement, even when Pearl (The Lost inflammation of the epidermis), the dermis is a persistent inflammatory process of the vessels.
In addition, an outbreak of inflammation in the development plays a role in psoriasis, activated T-lymphocytic cells, neurotransmitters, inflammatory reactions, inflammation in accordance with mikrozirkulation. In the study of the skin microflora streptococci occur in patients with psoriasis, psoriasis and general guttat to provoke.
The development of the immunological basis of the pathogenesis of psoriasis, progress IleD4 activates immune cells+ T-lymphocytic cells and cytokines with an anti-inflammatory effect. As a token of this theory, monoclonal antibodies, psoriasis, active against applicable IleD4+ T-lymphocytic cells with significant therapeutic effect. In addition, psoriasis is an effective remedy – aimed at inhibition of tumor necrosis factor to produce these drugs.
Psoriasis is contagious, surrounding skin
No. Psoriasis is a genetic disease.
Psoriasis is passed from person to person
No. Psoriasis becomes infected, it is impossible for another human being. Strep infection can act though-provoking factor, the formation of a man's genetic predisposition to diseases, psoriasis does not occur.
Passed psoriasis sexually transmitted
No. Psoriasis is not contagious, and any air drops are passed, no communication, sexual, nor in any other way.
Psoriasis is hereditary, passed
For psoriasis necessary for the development of genetic (hereditary) predisposition. For this reason, close relatives with the disease. If you have psoriasis, parents, and children grades a high risk of psoriasis.
However, some authors such as psoriasis is the second type of features separately. Suppose this option in patients who develop psoriasis after forty years, and that's mostly joints and the nail plate, heredity is associated with.
Die psoriasis can I get
No. Psoriasis is not a life threatening disease. Estimated life for these patients is positive.
However, psoriasis significantly hampers full-fledged to cheer up the life of a patient, reducing him a lot of discomfort, and social activity.
Also, it should be noted that the form pustular psoriasis can be extremely difficult, drop discharge, and inflammation of pimples, according to your skin type inflamed more falling away "lakes". In this case, may develop eritroderma, secondary bacterial complications, joint involvement, etc.
Precipitating factors of psoriasis development
The basic factors contributing to the emergence of acute psoriasis, are as follows:
- injury to the skin;
- endocrine disorders;
- pregnancy;
- view of metabolic disorders;
- the use of the drug, beta-blockers, anti-malaria wed -, etc.;
- the presence of foci of chronic infection, streptococcal infection);
- alcohol beverages;
- cigarette;
- excessive sunbathing;
- use, spicy, sugary, oily, etc. foods;
- acute infectious disease;
- acute allergic diseases;
- stress, emotional overload (psoriasis border when it escalates in the soil, most often).
Classification psoriasis
Form psoriasis and types of features such as:
- vulgaris (common form, psoriasis);
- exudative;
- tiryaki, palmar-plantar;
- warts;
- follicular;
- quotation;
- pustular;
Construction you can wear during the course of the disease, hard character.
Lesions limited amenities such as the prevalence, widespread and common throughout.
Also, there may be flammability seasonality: winter, summer, and ambiguous (not the season) with acute psoriasis.
Photo, symptoms and treatment of psoriasis in adults
The characteristic appearance of psoriasis can be controlled popular pinkish or bright red, plated silver color, with whitish scales, a loose consistency. Itching, the skin may be missing. Celebrating the emergence of many patients, tightness, skin.
Characterized by intense itching, usually with psoriatic lesions on the skin, scalp, and groin.
Emergence in the development of psoriatic arthritis joint pains, celebrated.
The most characteristic symptoms of psoriasis, specific symptoms triad :
- the emergence of the phenomenon their point of (gain popular diagnosis during peeling psoriasis causes similar drop stearin);
- terminal view a movie (to view thin, transparent film, then peeling the remaining will all be leaving podkabluchnik);
- that occur blood, the dew point or the last point in the RET terminal bleeding somewhere movies.
Popular insulated air or psoriatic merge. The size may vary a little - covering up a wide skin surface. The most common localizations are popular, elbows, knees, head (the head part) and waist.
In rare cases, the plaque may also affect mucous membranes, lips and oral cavity.
Children, the elderly, and individuals with diabetes, the folded shape can develop disease. In such a case, the affected skin, behind the ear, under the arm, perineum, gluteal folds, the navel, around and under the mammary glands.
Psoriasis patients this may not be peeling. Foci of psoriatic plaques may be completely smooth surface, bright red. In some cases, maceration may be caused folds.
Plaques may be only a manifestation of the disease in some patients, skin and mucous genital organs.
Usually, symmetric psoriatic skin lesions is worn is a character, but some of the rashes observed in patients with unilateral. Psoriatic plaques may also result in muscular foci (ring, curved, geographical, etc.).
In patients with prolonged flowing disease, long-term existing plaque may be accompanied by lumbar and gluteal region skin the advent warty growths on them.
In addition, the warty form of psoriasis can serve reasons:
- purulent infection of the skin;
- wrong dental treatment (usually self-treatment);
- excessive body weight.
A warty forms of the disease, we must unite with each other forming plaques on the surface of scales begins with a yellow shell.
Flowing isolation may occur in some patients, palmar-plantar psoriasis. In this case, the patient uncomfortable, painful cracks, pustules, popular, erythematous-scaly plaques of the palms and feet.
A frequent manifestation of psoriasis in nail plates a defeat. In most cases, the appearance of pits on the surface of the nail the spot notes (dystrophy). You might look at, wrinkles longitudinal and transverse deformation of a nail, thickening of nail, discoloration, loosening and bleeding under the nail plate.
Erythrodermic psoriasis is a developing, usually on a background of excessive sun exposure or incorrect dental treatment, visible, apparent, skin edema, hyperemia, and desquamation, severe itching, fever, fatigue, loss of appetite. May cause severe anemia, heart failure, and kidney and liver, visible dehydration, alopecia areata.
Psoriasis and pregnancy is a threat to the child characteristics of
Reproductive function psoriasis and the service in violation of contraindications pregnancy. Needless to say, many women during pregnancy is a disease is usually easier. However, there may be a distinct disease aggravation of approximately twenty percent women.
In general, psoriasis is not difficult and pregnancy is not life-threatening child. However, in patients with arthritis, increased load, joint, and there may be a significant deterioration. Forms of generalized pustular psoriasis that can be caused by a secondary bacterial complications.
Because psoriasis doesn't mean it should not be forgotten, communicable diseases, maternal and smoothly contact with a child and breastfeed him. The possibility psoriasis child in the future equal to approximately 15-20%, a patient, a parent, and 50%, if both parents of the patient.
The main difficulty is contra-indicated to them that she was pregnant the most prescribed psoriasis medications. Warn in advance when you plan pregnancy, your doctor is a treatment method to this preset.
Ilesamolechenie is absolutely unacceptable, as a significant harm and damage the mother and baby (fetus toxic effects with some drugs).
Disease diagnosis
Exposure diagnosis on the basis of specific symptoms (psoriatic triad). Also, if necessary, histological data, radiological and immunological research.